Phase I of this new state-of-the-art, multi-disciplinary research facility for the University of Louisville's Health Sciences Center Campus consists of a $35,000,000, four-story structure with a full basement and roof mechanical penthouses. The facility is connected to the existing 11-story research tower with a bridge over Abraham Flexner Way at the second level of the new facility. No future vertical expansion is considered in the current design. The exterior wall system consists of a combination brick fascia, backed with light-gauge stud framing and storefront window construction.

The floor and roof structure is composite slab and beam construction. Lateral load resistance is provided by braced frames strategically located within the building to resist the code-prescribed wind and seismic loads. The foundation system consists of Auger cast piles. During schematic design, both concrete and steel options were considered from cost and vibration sensitivity standpoints. Both being relatively equal, a composite steel structure was chosen to allow column-free auditorium and lobby spaces in the lower level of the facility.

Phase II, currently under construction, mirrors the Phase I footprint and will house similar facilities, including an expanded Animal Holding area. Various design and configuration options were considered for this second facility, also $35,000,000. Arrasmith Judd Rapp of Louisville, Kentucky is the project's architect.